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摘要
A new aptamer-based fluorescence nanoprobe for potassium ion (K(+)) has been developed. The nanoprobe employs gold nanoparticles (AuNPs) as the sensing platform and Rhodamine B as the fluorescence indicator. Aptamer acts as the switch of fluorescence signal of Rhodamine B. In the presence of K(+), aptamer departs from AuNPs as a result of the formation of G-quartets with K(+), leading to the decrease of fluorescence signals. Under the optimum conditions, the limit of detection (LOD) for K(+) is as low as 3.8 nM. The proposed method was successfully applied in the determination of K(+) in human saliva sample.
- 出版日期2011
- 单位青岛科技大学
