Absent ductus venosus: case series from two tertiary centres

作者：Maruotti Giuseppe Maria; Saccone Gabriele; Ciardulli Andrea; Mazzarelli Laura Letizia; Berghella Vincenzo^*; Martinelli Pasquale

来源：Journal of Maternal-Fetal and Neonatal Medicine, 2018, 31(18): 2478-2483.

DOI：10.1080/14767058.2017.1344637

• Ductus venosus agenesis
• prenatal diagnosis
• ultrasonography

Introduction: Congenital absence of the ductus venosus (ADV) is a rare vascular anomaly often associated with fetal cardiac and extracardiac anomalies, aneuploidies, and hydrops. The prognosis depends on the patterns of abnormal venous circulation, on the associated malformations and on chromosomal aberrations.Methods: We performed a retrospective audit of all consecutive cases with ADV referred in our centres and analysed the outcomes.Results: A total of six cases with prenatally diagnosed ADV were identified. The gestational age at diagnosis ranged from 15 to 35 weeks. Karyotyping was performed in all cases. Normal karyotype was found in five out of the six cases. Overall, four neonates survived at 28 days follow-up. The other two died 48h after delivery: both of them had extrahepatic ADV.Discussion: Absence of the ductus venosus may be compatible with normal fetal development without relevant disturbance of circulation and oxygenation independently from type of abnormal venous circulation.

• 出版日期2018