SOCIODEMOGRAPHIC AND CLINICAL PROFILE OF PATIENTS WITH MYELODYSPLASTIC SYNDROMES

作者：Ferreira Marcos Antonio Jr^*; Ivo Maria Lucia; Jardim Cury Pontes Elenir Rose; de Souza Rego Pinto Carvalho Diana Paula; Vitor Allyne Fortes

来源：Bioscience Journal, 2014, 30(4): 1269-1277.

• Preleukemia
• Anemia refractory
• Anemia refractory with excess of blasts
• Epidemiology
• Demographic Aging

Epidemiological studies on Myelodysplastic Syndromes (MDS) are not found in Brazilian literature, which requires investigation of this prevalent disease in the elderly and higher incidence with increasing age. This study aimed to investigate the sociodemographic and clinical characteristics of patients with MDS to characterize this population at a referral center for high complexity. It is a cross-performed from January 2000 to December 2010. For descriptive analysis was conducted using Epi Info 2002, version 3.5.2. The calculations of the likelihood of association between the characteristics analyzed and gender were performed using the chi-square, Fisher and Fisher's Exact. The level of significance was 0.05. The study was approved in its ethical aspects and the methodological Ethics Committee in Research ECR/HUOL Protocol 432/10. We selected 29 patients. The sample was characterized mainly by elderly male with lower education, who had anemia as initial symptom. Most were white-skinned people living in their own homes, residents in urban areas and with income less than two minimum wages. All blood products used therapy, especially red blood cells, a frequency of four or more units per month of consumption. Only 20% performed dosage of serum ferritin, all with values referenced above normal. We conclude that it is necessary to conduct research with larger populations, multicenter character in order to best evidence on the demographic data and clinical evaluation with the possibility of the country.

• 出版日期2014-8