MRI Reveals Brain Abnormalities in Drug-Naive Parkinson's Disease

作者:Planetta Peggy J; McFarland Nikolaus R; Okun Michael S; Vaillancourt David E*
来源:Exercise and Sport Sciences Reviews, 2014, 42(1): 12-22.
DOI:10.1249/JES.0000000000000003

摘要

Most brain studies of Parkinson's disease (PD) focus on patients who are already taking antiparkinsonian medication. This makes it difficult to isolate the effects of disease from those of treatment. We review magnetic resonance imaging evidence supporting the hypothesis that early-stage untreated PD patients have structural and functional abnormalities in the brain, some of which are related to motor symptoms.

  • 出版日期2014-1