A retrospective audit of 200 cases of CNS tumours and their surgical management in a tertiary care centre

作者：Nor F E Muhamat^*; Chandrasekaran K; Marks J C

来源：Irish Journal of Medical Science, 2013, 182(4): 697-701.

DOI：10.1007/s11845-013-0959-1

• Central nervous system tumours
• Operative mortality
• Operative morbidity
• Presenting features
• Cork University Hospital
• Neurosurgery

To study the nature of the tumours managed in the Irish population. %26lt;br%26gt;This audit research was completed via a retrospective medical review on 200 patients with CNS tumours managed in a tertiary care centre between 2008 and 2009. %26lt;br%26gt;The mean age was 53 years. The male:female ratio was 2:1. The majority were glioblastomas and astrocytomas. Grade IV tumours were predominant (65.5 %). Headaches (37 %), motor weakness (32 %) and seizures (25.5 %) were the highest presentations. The commonest sites affected were the left parietal and left temporal lobes. There were 17.5 % operative morbidities with motor weakness (22.9 %), seizure (14.3 %) and thrombo-embolism (14.3 %) dominating and significant association to surgical radicality (p = 0.041). 3.5 % operative mortalities were reported. 52.5 and 62.5 % of patients received adjuvant chemotherapy and radiotherapy, respectively. %26lt;br%26gt;Patients with CNS tumours typically had multiple presentations. More extensive surgical resection was associated with higher postoperative morbidities (p = 0.041). The 30-day postoperative morbidity (17.5 %) and mortality (3.5 %) were concordant with the currently available literature.

• 出版日期2013-6