Pharmacological effects of Astragaloside IV: a literature review

作者：Ren Shuang; Zhang Hua; Mu Yongping; Sun Mingyu; Liu Ping^*

来源：Journal of Traditional Chinese Medicine, 2013, 33(3): 413-416.

DOI：10.1016/s0254-6272(13)60189-2

• Astragaloside IV
• Extraction
• Pharmacokinetics
• Pharmacology

OBJECTIVE: To review the pharmacological effect and mechanisms of action of Astragaloside IV in Huangqi (Radix Astragali Mongolici).
METHODS: Aticles focusing on Astragaloside IV in English and Chinese in databases were collected and reviewed in order to summarize the latest extraction separation, pharmacokinetics, and the pharmacological effects of astrageloside IV.
RESULTS: Protective effects of Astrageloside IV on the cardiovascular system, immune, digestive, nervous system were identified, and the action mechanisms were associated with regulation of the calcium balance, anti-oxydant, antiapoptosis, antivirus, and so on.
CONCLUSION: Astrageloside IV has broad application prospects, especially in cardiovascular diseases, digestive diseases, cancer and other modern high incidence, high-risk diseases, and could be developed as a medicine.

• 出版日期2013-6-15
• 单位上海中医药大学