Allergy to exotic fruits

作者：Hemmer W^*; Litschauer Poursadrollah M; Sesztak Greinecker G; Woehrl S; Wantke F; Jarisch R

来源：Allergologie, 2012, 35(7): 373-386.

DOI：10.5414/ALX01464

• fruit allergy
• secondary food allergy
• cross-reactivity
• fig
• jackfruit
• persimmon
• mango
• lychee
• papaya

Allergy to exotic fruits
Allergic reactions to exotic fruits are relatively rare, but an increasing number of cases might be expected in view of the ever increasing availability, affordability and assortment of such fruits in Central Europe. Most cases of allergic reactions to tropical fruits represent examples of secondary food allergy with many of the implicated foods showing immunologic relationships with more than one primary sensitizer. The scale of exotic fruit allergy might be exceptionally complex in Central Europe due to the high diversity of locally relevant indoor and outdoor allergens associated with food hypersensitivity. Apart from latex allergy, also sensitization to birch or mugwort pollen is commonly associated with adverse reactions to tropical fruits. PR-10 allergens cross-reactive with the major birch pollen allergen Bet v 1 have been identified in kiwi, persimmon, fig and jackfruit. Some cases of anaphylaxis from mango and lychee appear to be related to concomitant mugwort pollen allergy. Profilins have been described as relevant allergens in pineapple, banana, mango, lychee, and melons. Sensitization to Ficus benjamina is commonly associated with fig fruit allergy. The responsible allergens, cysteine proteases, show partial cross-reactivity with homologous allergens in kiwi (Act d 1), papaya, pineapple, and banana. Lipid transfer proteins (nsLTP) have been identified in kiwi, banana and pitaya and might represent relevant allergens also in other tropical fruits. Still little is known about the significance of other potentially relevant protein families, such as thaumatin-like proteins, isoflavone reductases, cyclophilins, and pectinesterases. The present paper describes 15 patients with allergic reactions to tropical fruits, including fig, jackfruit, mango, lychee, persimmon and papaya. Primary sensitization to birch pollen (Bet v 1), mugwort pollen, profilins as well as Ficus benjamina and papain was identified as the cause of the reactions.

• 出版日期2012-7