A Wireless Magnetoelastic Sensor for Urinary 2-Naphthol Detection Based on the Precipitation of 2-Naphthol with Diazonium Salts

作者：Yuan, Yu Kun; Wang, Yong Sheng^*; Xiao, Xi Lin; Xue, Jin Hua; Li, Gui Rong; Kang, Rong Hui; Zhang, Jin Quan; Shi, Lin Fei

来源：Analytical Sciences, 2011, 27(5): 517-521.

DOI：10.2116/analsci.27.517

A wireless magnetoelastic sensor has been developed for the determination of 2-naphthol (2-NAP) in human urine. This method is based on the precipitation of 2-NAP with diazonium salts produced by the diazo-reaction of sulfamethoxazole (SMZ) with nitrite under a weak alkaline condition, resulting in a descending of the resonance frequency of a wireless magnetoelastic sensor. The frequence shift values (Delta F) of the sensor were directly proportional to the concentration in the range of 1.13 - 139 mu mol L(-1) for 2-NAP with a correlation coefficient of 0.997 and a detection limit of 0.340 mu mol L(-1). The relative standard deviations were 2.38, 2.40 and 2.44%, and the average recovery was 107% (n = 6). The proposed method has additional advantages of being less time-consuming, low cost and remote query, and can be applied for real-time and in situ monitoring of 2-NAP in human urine. It would be a benefit to extend the scope of applications of magnetoelastic sensing techniques.

• 出版日期2011-5
• 单位南华大学