A synthesis of alpha-amino acids via direct reductive carboxylation of imines with carbon dioxide

作者:Sathe Ajay A; Hartline Douglas R; Radosevich Alexander T*
来源:Chemical Communications, 2013, 49(44): 5040-5042.
DOI:10.1039/c3cc42057d

摘要

A method for the synthesis of alpha-amino acids by direct reductive carboxylation of aromatic imines with CO2 is described. The protocol employs readily available commercial reagents and serves as a one-step alternative to the Strecker synthesis.

  • 出版日期2013

全文