A tetracyclic thiophene trimer synthesis and mechanism of formation

作者：Berner Heinz; Erker Thomas^*; Handler Norbert; Leisser Klaus; Nemec Stephanie; Reischl Wolfgang; Wurst Klaus

来源：Tetrahedron Letters, 2013, 54(21): 2696-2698.

DOI：10.1016/j.tetlet.2013.03.071

• 2,5-Dimethylthiophene
• Trimerization
• Quantum-chemical calculation
• Mechanism

Under strong acidic conditions, 2,5-dimethylthiophene forms a tetracyclic trimer almost quantitatively whose peculiar structure could be elucidated by X-ray analysis. In addition, by means of quantum mechanical calculations, a sound mechanistic picture of the reaction pathway is proposed.

• 出版日期2013-5-22