Advances in chronic obstructive pulmonary disease among older adults

作者：Blanchette Christopher M^*; Berry Susan R; Lane Sandi J

来源：Current Opinion in Pulmonary Medicine, 2011, 17(2): 84-89.

DOI：10.1097/MCP.0b013e32834316ff

• chronic obstructive pulmonary disease
• elderly
• older adults

Purpose of review
This review summarizes recent research on chronic obstructive pulmonary disease (COPD) among older adults.
Recent findings
Recent research on COPD and older adults addresses four key areas: diagnosis and screening, comorbidities, end-of-life care, and management. These key findings include the Rotterdam study's identification of the incidence rate of COPD in older adults being 9.2 per 1000 person-years; a new assessment of FEV1 cut-points associated with increased prevalence of respiratory symptoms and risk of death; development and validation of new mortality scales, the ADO (age, dyspnea, and airflow obstruction) index and the PILE score; older adults with COPD average 9 comorbidities, of which depression, cardiovascular diseases such as hypertension, and chronic renal failure are highly prevalent; nonrespiratory treatments such as proton pump inhibitors, angiotensin-converting enzyme inhibitors, and statins show promise in the management of COPD; and strength may be a protective factor for older adults with COPD.
Summary
Findings suggest that more research on older adults and COPD suggest that aging is a determinant of the progression of disease and that management of this population requires different metrics and strategies.

• 出版日期2011-3