Accelerated Calcium Phosphate Formation on Titanium Utilizing Galvanic Current between Titanium and Gold in Hanks%26apos; Solution

作者：Tsutsumi Yusuke^*; Kobayashi Equo; Ogo Masakimi; Suyalatu; Migita Satoshi; Doi Hisashi; Nomura Naoyuki; Noda Kazuhiko; Hanawa Takao

来源：Materials Transactions, 2013, 54(2): 149-155.

DOI：10.2320/matertrans.MC201204

• titanium
• galvanic current
• calcium phosphate
• hard-tissue compatibility

To enhance hard-tissue compatibility of Ti, galvanic current between titanium ( Ti) and gold ( Au) may be available. Prior to the design of medical devices with the capability to generate a galvanic current, it is necessary to understand the control mechanism. In this study, we first measured galvanic current between Ti and Au with various surface areas in Hanks%26apos; solution. The galvanic current increased immediately after connection of two electrodes, followed by an abrupt decrease and a steady state. The galvanic current varied with the combinations of Ti and Au areas. We, thereafter, evaluated the formation of calcium phosphate on Ti under a condition of applying simulated galvanic current. Surface characterization was revealed in which the calcium phosphate formation was enhanced accompanied by growth of Ti oxide layer under the galvanic current application. A similar result was observed on Ti with patterned Au coating without outer electric power. Therefore, galvanic current is useful to enhance hard-tissue compatibility, and this technique has potential for applications to metallic biomaterials.

• 出版日期2013