Association between Feeding Difficulties and Language Delay in Preterm Infants Using Bayley Scales of Infant Development-Third Edition

作者：Adams Chapman Ira^*; Bann Carla M; Vaucher Yvonne E; Stoll Barbara J

来源：Journal of Pediatrics, 2013, 163(3): 680-+.

DOI：10.1016/j.jpeds.2013.03.006

Objective To evaluate the relationship between abnormal feeding patterns and language performance on the Bayley Scales of Infant Development-Third Edition at 18-22 months adjusted age among a cohort of extremely premature infants.
Study design This is a descriptive analysis of 1477 preterm infants born <= 26 weeks gestation or enrolled in a clinical trial between January 1, 2006 and March 18, 2008 at a National Institute of Child Health and Human Development Neonatal Research Network center who completed the 18-month neurodevelopmental follow-up assessment. At 18-22 months adjusted age, a comprehensive neurodevelopmental evaluation was performed by certified examiners including the Receptive and Expressive Language Subscales of the Bayley Scales of Infant Development-Third Edition and a standardized adjusted age feeding behaviors and nutritional intake. Data were analyzed using bivariate and multilevel linear and logistic regression modeling.
Results Abnormal feeding behaviors were reported in 193 (13%) of these infants at 18-22 months adjusted age. Abnormal feeding patterns, days of mechanical ventilation, hearing impairment, and Gross Motor Functional Classification System level >= 2 each independently predicted lower composite language scores.
Conclusions At 18 months adjusted age, premature infants with a history of feeding difficulties are more likely to have language delay. Neuromotor impairment and days of mechanical ventilation are both important risk factors associated with these outcomes.

• 出版日期2013-9