Highly stereo-selective synthesis of (Z)-2,3-diiodo-1,4diarylbut-2-ene-1,4-diones via oxidative iodination of 1,4-diarylbuta-1,3-diynes

作者：Singha Raju^*; Dhara Shubhendu; Ray Jayanta K

来源：RSC Advances, 2013, 3(46): 23989-23992.

DOI：10.1039/c3ra44965c

A novel and highly stereo and regioselective oxidative iodination of 1,4-diarylbuta-1,3-diynes promoted by N-iodosuccinamide results in (Z)-2,3-diiodo-1,4-diarylbut-2-ene-1,4-diones. In the case of NBS, the stereo-selectivity is moderate while NIS gives exclusively Z product. A plausible mechanism for the formation of both E and Z products is also proposed.

• 出版日期2013