Novel and established intestinal cell line models - An indispensable tool in food science and nutrition

作者:Langerholc Tomaz; Maragkoudakis Petros A; Wollgast Jan; Gradisnik Lidija; Cencic Avrelija*
来源:Trends in Food Science & Technology, 2011, 22: S11-S20.
DOI:10.1016/j.tifs.2011.03.010

摘要

This review presents the applications of intestinal cell models of human and pig origin in food and nutritional sciences and highlights their potential as in vitro platforms for preclinical research. Intestinal cell models are used in studies of bioavailability, adsorption and transport in nutritional or toxicological settings, allergic effects of food components, as well as probiotics and/or host-pathogen gut interactions. In addition, this review discusses the advantages of using specialized and functional cell models over generic cancer-derived cell lines.

  • 出版日期2011-11