Branched silica nanostructures oriented by dynamic G-quadruplex transformation

作者:Zhang Jinli; Zheng Lin; Wang Xian; Xiao Ying; Lu Yi; Li Wei*
来源:Materials Research Bulletin, 2010, 45(12): 1954-1959.
DOI:10.1016/j.materresbull.2010.08.008

摘要

Polymorphic G-quadruplexes including stacked G-quartet planes are potentially promising DNA templates beyond Watson-Crick duplexes to construct inorganic nanostructures. In this work, a novel G-rich oligonucleotide that can be modulated from the antiparallel G-quadruplex to multi-stranded supermolecular assemblies was designed. Based on this dynamic G-quadruplex transformation, an interesting leaf-vein silica nanostructure with regular branched intervals was constructed. The G-quadruplex assembly structure was found to play a significant role in the organization of the silica structures.