Brain disorders: getting 'Down' to the gene

作者：Tessarollo Lino^*

来源：Nature Neuroscience, 2010, 13(8): 909-910.

DOI：10.1038/nn0810-909

Narrowing down the genetic basis of Down syndrome, in which hundreds of genes are triplicated, has been difficult. A new study finds that the expression of two affected genes, Olig1 and Olig2, is critical for maintaining the balance of inhibitory and excitatory signaling in a mouse model of Down syndrome.

• 出版日期2010-8