Highly Regioselective Double Hydrothiolation of Terminal Acetylenes with Thiols Catalyzed by Palladium Diacetate

作者:Mitamura Takenori; Daitou Masayuki; Nomoto Akihiro; Ogawa Akiya*
来源:Bulletin of the Chemical Society of Japan, 2011, 84(4): 413-415.
DOI:10.1246/bcsj.20100311

摘要

Treatment of terminal acetylenes 1 with two equivalents of thiols 2 in the presence of Pd(OAc)(2) catalyst and H2O causes regioselective double hydrothiolation of 1, leading to the corresponding dithioketals 3 in moderate to good yields.

  • 出版日期2011-4-15