科研之友
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摘要
Umpolung is a fundamental concept in organic chemistry, which provides an alternative strategy for the synthesis of target compounds which were not easily accessible by conventional methods. Herein, a mild and efficient PhI(OAc)(2)-promoted umpolung acetoxylation reactions of enamides was developed for the synthesis of alpha-acetoxy ketones. The reaction tolerates a wide range of functional groups and affords alpha-acetoxy ketones in good to excellent yields. PhI(OAc)(2) serves as a source of acetoxy in the reaction.
- 出版日期2017-6
- 单位西北大学
