A randomized trial of two home-based exercise programmes to improve functional walking post-stroke

作者：Mayo Nancy E^*; MacKay Lyons Marilyn J; Scott Susan C; Moriello Carolina; Brophy James

来源：Clinical Rehabilitation, 2013, 27(7): 659-671.

DOI：10.1177/0269215513476312

• Stroke
• exercise
• rehabilitation
• mobility
• participation
• health-related quality of life

Objective: %26lt;br%26gt;To estimate the relative effectiveness in improving walking ability and other mobility and health outcomes post-stroke of two home-based exercise programmes - stationary cycling and an exercise and walking programme. %26lt;br%26gt;Design: %26lt;br%26gt;An observer-blinded, randomized, pragmatic, trial with repeated measures. %26lt;br%26gt;Setting: %26lt;br%26gt;Hospital centers in two Canadian cities. %26lt;br%26gt;Subjects: %26lt;br%26gt;People within 12 months of acute stroke who were able to walk %26gt;10 meters independently and healthy enough to engage in exercise. %26lt;br%26gt;Interventions: %26lt;br%26gt;Two dose-equivalent interventions, one involving stationary cycling and the other disability-targeted interventions were tested. Both protocols required daily moderate intensity exercise at home building up to 30 minutes per day. One group exercised on a stationary bicycle, the second group carried out mobility exercises and brisk walking. %26lt;br%26gt;Main measures: %26lt;br%26gt;The primary outcome was walking capacity as measured by the six-minute walk test (6MWT). Secondary outcomes were physical function, role participation, health-related quality of life exercise adherence, and adverse events. %26lt;br%26gt;Results: %26lt;br%26gt;The study failed to meet recruitment targets: 87 participants (cycle group, n = 43; exercise group, n = 44) participated. No significant effects of group or time were revealed for the 6MWT, which was approximately 320 m at randomization. A significant effect for role participation was found in favor of the exercise group (global odds ratio (OR) for cycling vs. exercise was 0.51; 95% confidence interval (CI), 0.27-0.95). Change in the 6MWT between highest and lowest adherence categories was statistically significant (p = 0.022). %26lt;br%26gt;Conclusions: %26lt;br%26gt;Both programmes were equally effective in maintaining walking capacity after discharge from stroke rehabilitation; or were equally ineffective in improving walking capacity.

• 出版日期2013-7