科研之友
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摘要
17 biallelic markers located in the nonrecombining portion of Y chromosome were typed by using ASPCR or PCR in 5 Chinese populations, Nu, Lisu, Naxi, Sala and She. The individuals' haplotypes derived from these 17 biallelic markers were constructed. The principle component (PC) analysis was conducted based on the haplotypes' frequencies of these 5 and 20 other published Chinese populations. The result showed that there were different frequencies at 12 markers, YAP, M15, M89, M9, M119, M95, M88, M45, M122, M134, M17 and M120 in the 5 populations except M50, M110, M03, M3 and M7, for their diversities were absent in the 5 populations. The M122 (C) frequencies of the Nu, Lisu, Naxi, Sala and She were 82.1, 31.6, 5.9, 20 and 69.3, respectively. Among the 5 populations, YAP+ was only found in Sala with 2.2 frequency, and Lisu had the highest M95 (T) frequency, 68.4. A total of 12 haplotypes (H1, H3, H4, H5, H6, H8, H9, H11, H12, H13 , H14 and H16) were observed in the 5 populations. The major haplotype frequencies of the 5 populations distributed among H5, H6, H8, H11 and H12. The result from PC analysis displayed that Lisu and the Hmong - Mein speaking populations consisted of group A; She, Nu, Hans (including Hakka) and other populations were clustered into group B ; Sala, Naxi and the Tibeto - Burman or Altaic speaking populations formed group C.
- 出版日期2006
- 单位中国医学科学院北京协和医院
