摘要

Six new dolabrane-type diterpenoids, notolutesin K-P (1-6), were isolated from the Chinese liverwort Notoscyphus collenchymatosus, along with five known dolabrane derivatives and a known pimarane derivative. Their structures were elucidated on the basis of extensive analysis of spectroscopic data. Cytotoxicity test against a panel of human cancer cell lines demonstrated that compound 6 showed cytotoxic activity with IC50 values range from 3.50 to 5.20 mu M.