Mild basic ionic liquid catalyzed four component synthesis of functionalized benzo[a]pyrano[2,3-c]phenazine derivatives

作者：Shaterian Hamid Reza^*; Mohammadnia Majid

来源：Journal of Molecular Liquids, 2013, 177: 162-166.

DOI：10.1016/j.molliq.2012.11.006

• Aldehydes
• Malononitrile
• Ionic liquid
• Catalyst
• o-Phenylenediamine
• Base

An efficient, mild, and one-pot quantitative procedure for the preparation of functionalized benzo[a]pyrano[2,3-c] phenazine derivatives from four component reaction of 2-hydroxynaphthalene-1,4-dione, o-phenylenediamine, aldehydes, and malononitrile in the presence of basic ionic liquids such as 1-butyl-3-methylimidazolium hydroxide, 3-hydroxypropanaminium acetate, pyrrolidinium formate, pyrrolidinium acetate, 1,8-diazabicyclo[5.4.0]-undec-7-en-8-ium acetate, and piperidinium formate as the catalysts has been developed. The ionic liquid was stable during the reaction process and could also be reused several times with consistent activity. This procedure may be a practical alternative to the existing one reported procedure to meet the need of academe as well as industries.

• 出版日期2013-1