Access to Cyclic or Branched Peptides Using Bis(2-sulfanylethyl)amido Side-Chain Derivatives of Asp and Glu

作者：Boll Emmanuelle; Dheur Julien; Drobecq Herve; Melnyk Oleg^*

来源：Organic Letters, 2012, 14(9): 2222-2225.

DOI：10.1021/ol300528r

Bis(2-sulfanylethyl)amido (SEA) side-chain derivatives of aspartic and glutamic acids enable the synthesis of tail-to-side chain cyclic or branched peptides using standard Fmoc-SPPS followed by SEA native peptide ligation.

• 出版日期2012-5-4