Application of MALDI Mass Spectrometry in Natural Products Analysis

作者：Silva Ricardo; Lopes Norberto Peporine; Silva Denise Brentan

来源：Planta Medica, 2016, 82(8): 671-689.

DOI：10.1055/s-0042-104800

• MALDI
• dereplication
• natural products
• fragmentation
• data processing

This article presents the utility of mass spectrometry with a MALDI ionization source in natural products analysis. The advantages and drawbacks of this technique for natural products analyses will be presented and discussed. In addition, the structural determination of secondary metabolites using MALDI-MS/MS will be explored, which can guide MALDI experimental methods and stimulate new research in this area. Finally, several important approaches for MALDI data processing will be discussed.

• 出版日期2016-5