Branching Feller diffusion for cell division with parasite infection

作者：Bansaye Vincent^*; Viet Chi Tran

来源：Alea (Rio de Janeiro): Latin American Journal of Probability and Mathematical Statistics , 2011, 8: 95-127.

• Branching Process
• Feller diffusion
• Multiplicative jumps
• Parasite infection

We describe the evolution of the quantity of parasites in a population of cells which divide in continuous-time. The quantity of parasites in a cell follows a Feller diffusion, which is splitted randomly between the two daughter cells when a division occurs. The cell division rate may depend on the quantity of parasites inside the cell and we are interested in the cases of constant or monotone division rate. We first determine the asymptotic behavior of the quantity of parasites in a cell line, which follows a Feller diffusion with multiplicative jumps. We then consider the evolution of infection in the cell population and give criteria to determine whether the proportion of infected cells goes to zero (recovery) or if a positive proportion of cells becomes largely infected (proliferation of parasites inside the cells).

• 出版日期2011