Hepatitis C Core Antigen Testing: A Reliable, Quick, and Potentially Cost-effective Alternative to Hepatitis C Polymerase Chain Reaction in Diagnosing Acute Hepatitis C Virus Infection

作者：Cresswell Fiona V^*; Fisher Martin; Hughes Daniel J; Shaw Simon G; Homer Gary; Hassan Ibrahim Mohammed O

来源：Clinical Infectious Diseases, 2015, 60(2): 263-266.

DOI：10.1093/cid/ciu782

• acute hepatitis C
• hepatitis C core antigen
• PCR
• diagnosis

Hepatitis C virus (HCV) is increasingly common among human immunodeficiency virus (HIV)-infected men who have sex with men. We evaluated the efficacy of HCV core antigen in diagnosing acute HCV in an HIV-infected cohort. Compared with HCV polymerase chain reaction, core antigen proved sensitive (100%) and specific (97.9%). As a quick, simple, and cost-effective test, it has considerable utility in screening for acute HCV.

• 出版日期2015-1-15