Soy Allergy Following Early Soy Feeding in Neonates

作者：Nachmias Nimrod; Landman Yaakov; Danon Yehuda L; Levy Yael^*

来源：Israel Medical Association Journal, 2010, 12(11): 684-686.

• food allergy
• neonates
• soy
• oral tolerance

Background Feeding neonates with humanized milk formula in maternity hospitals may increase the prevalence of milk allergy in infants However, prospective studies of the possible allergenic effect of very early soy based formula feeding are lacking
Objectives To assess the prevalence of soy allergy in infants fed soy based formula in the first 3 days of life
Methods The study group included 982 healthy full term infants born within a 7 month period at a hospital that routinely uses soy based formula to supplement breastfeeding In hospital feeding was recorded and the parents were interviewed once monthly over the next 6 months regarding feeding practices and clinical symptoms suggesting soy allergy in the infant
Results Ninety nine percent of the infants received soy based formula supplement in hospital, and 33%-42% at home No cases of immediate allergic reaction to soy or soy induced enterocolitis were reported
Conclusions The use of soy based formula in the early neonatal period does not apparently increase the prevalence of soy allergy in infants followed for the next 6 months IMAJ2010, 12 684-686

• 出版日期2010-11