Short Communication: Fracture Risk by HIV Infection Status in Perinatally HIV-Exposed Children

作者：Siberry George K^*; Li Hong; Jacobson Denise

来源：AIDS Research and Human Retroviruses, 2012, 28(3): 247-250.

DOI：10.1089/aid.2011.0064

The objective of this study was to examine the incidence of fractures in HIV-infected children and comparable HIV-exposed, uninfected (HEU) children in a multicenter, prospective cohort study (PACTG 219/219C) in the United States. The main outcome was first fracture during the risk period. Nine fractures occurred in 7 of 1326 HIV-infected and 2 of 649 HEU children, corresponding to incidence rates of 1.2 per 1000 person-years and 1.1 per 1000 person-years, respectively. The incidence rate ratio was 1.1 (95% CI 0.2, 5.5). There was no evidence of a substantially increased risk of fracture in HIV-infected compared to HEU children.

• 出版日期2012-3
• 单位NIH