Antibacterial screening of traditional herbal plants and standard antibiotics against some human bacterial pathogens

作者：Awan Uzma Azeem; Andleeb Saiqa^*; Kiyani Ayesha; Zafar Atiya; Shafique Irsa; Riaz Nazia; Azhar Muhammad Tehseen; Uddin Hafeez

来源：Pakistan Journal of Pharmaceutical Sciences, 2013, 26(6): 1109-1116.

• Human bacterial pathogens
• antibacterial activity
• medicinal plants
• antibiotics
• agar disc diffusion assay
• activity index

Chloroformic and isoamyl alcohol extracts of Cinnnamomum zylanicum, Cuminum cyminum, Curcuma long Linn, Trachyspermum ammi and selected standard antibiotics were investigated for their in vitro antibacterial activity against six human bacterial pathogens. The antibacterial activity was evaluated and based on the zone of inhibition using agar disc diffusion method. The tested bacterial strains were Streptococcus pyogenes, Staphylococcus epidermidis, Klebsiella pneumonia, Staphylococcus aurues, Serratia marcesnces, and Pseudomonas aeruginosa. Ciprofloxacin showed highly significant action against K pneumonia and S. epidermidis while Ampicillin and Amoxicillin indicated lowest antibacterial activity against tested pathogens. Among the plants chloroform and isoamyl alcohol extracts of C. cyminum, S. aromaticum and C. long Linn had significant effect against P aeruginosa, S. marcesnces and S. pyogenes. Comparison of antibacterial activity of medicinal herbs and standard antibiotics was also recorded via activity index. Used medicinal plants have various phytochemicals which reasonably justify their use as antibacterial agent.

• 出版日期2013-11