Allergen immunotherapy for allergic rhinoconjunctivitis: protocol for a systematic review

作者：Dhami Sangeeta^*; Nurmatov Ulugbek; Roberts Graham; Pfaar Oliver; Muraro Antonella; Ansotegui Ignacio J; Calderon Moises; Cingi Cemal; Demoly Pascal; Durham Stephen; van Wijk Ronald Gerth; Halken Susanne; Hamelmann Eckard; Hellings Peter; Jacobsen Lars; Knol Edward; Larenas Linnemann Desiree; Lin Sandra; Maggina Vivian; Oude Elberink Hanneke; Pajno Giovanni; Panwankar Ruby; Pastorello Elideanna; Pitsios Constantinos; Rotiroti Giuseppina; Timmermans Frans

来源：Clinical and Translational Allergy, 2016, 6(1): 12.

DOI：10.1186/s13601-016-0099-6

• Allergy
• Allergic rhinoconjunctivitis
• Allergen immunotherapy
• Rhinitis

Background: The European Academy of Allergy and Clinical Immunology (EAACI) is in the process of developing the EAACI Guidelines for Allergen Immunotherapy (AIT) for the Management of Allergic Rhinoconjunctivitis. We seek to critically assess the effectiveness, cost-effectiveness and safety of AIT in the management of allergic rhinoconjunctivitis.
Methods: We will undertake a systematic review, which will involve searching international biomedical databases for published, in progress and unpublished evidence. Studies will be independently screened against pre- defined eligibility criteria and critically appraised using established instruments. Data will be descriptively and, if possible and appropriate, quantitatively synthesised.
Conclusion: The findings from this review will be used to inform the development of recommendations for EAACI's Guidelines on AIT.

• 出版日期2016-3-22