A novel cyclization/oxidation strategy for a two-step synthesis of (Z)-aurone

作者:Li Siyuan; Jin Feng; Viji Mayavan; Jo Hyeju; Sim Jaeuk; Kim Hak Sung*; Lee Heesoon; Jung Jae Kyung*
来源:Tetrahedron Letters, 2017, 58(14): 1417-1420.
DOI:10.1015/j.tetlet.2017.02.074

摘要

An efficient and facile two-step strategy for the synthesis of (Z)-aurone from arylacetylenes and salicyladehydes, via silver(I) nitrate mediated cyclizationioxidation in the presence of potassium carbonate has been developed. The key feature of our method was delicate cascade reaction, to provide the corresponding (Z)-aurone in high yield and good regio- and stereo selectivity.

  • 出版日期2017-4-5

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