A molecular approach to understanding human sterol metabolism using yeast genetics

作者:Sturley SL*
来源:Current Opinion in Lipidology, 1998, 9(2): 85-91.
DOI:10.1097/00041433-199804000-00002

摘要

The availability of the sequenced genome of Saccharomyces cerevisiae (yeast) has culminated in the use of this model eukaryote to study human diseases at a basic level. This article describes the advantages of studying lipid metabolism in this genetically facile organism, including examples of conserved functions and genetic approaches to identifying new components of cholesterol homeostasis.

  • 出版日期1998-4