New insights into cathelicidin modulation of adaptive immunity

作者:Wuerth Kelli; Hancock Robert E W*
来源:European Journal of Immunology, 2011, 41(10): 2817-2819.
DOI:10.1002/eji.201142055

摘要

Cathelicidins are a family of host defence peptides that are known to selectively alter innate immunity in response to infection and other changes in immune status. A study in this issue of the European Journal of Immunology elucidates a new role for mouse cathelin-related antimicrobial peptide in the adaptive immune response by clearly demonstrating for the first time that a cathelicidin can alter T-cell-dependent activation of the humoral response in vivo and thus modulate the activities of both B and T lymphocytes.

  • 出版日期2011-10