ADPr-ChAP: Mapping ADP-Ribosylation onto the Genome

作者：McPherson Robert Lyle; Leung Anthony K L^*

来源：Molecular Cell, 2016, 61(3): 327-328.

DOI：10.1016/j.molcel.2016.01.023

In this issue of Molecular Cell, Bartolomei et al. (2016) describe a chromatin affinity precipitation method using well-characterized ADP-ribose binding domains to provide the first genome-wide view of ADP-ribosylated chromatin. Here, we discuss its potential applications and the remaining challenges ahead.

• 出版日期2016-2-4