A METHOD FOR EXPLORATORY REPEATED-MEASURES ANALYSIS APPLIED TO A BREAST-CANCER SCREENING STUDY

作者:Brentnall Adam R*; Duffy Stephen W; Crowder Martin J; Gillan Maureen G C; Astley Susan M; Wallis Matthew G; James Jonathan; Boggis Caroline R M; Gilbert Fiona J
来源:Annals of Applied Statistics, 2011, 5(4): 2448-2469.
DOI:10.1214/11-AOAS481

摘要

When a model may be fitted separately to each individual statistical unit, inspection of the point estimates may help the statistician to understand between-individual variability and to identify possible relationships. However, some information will be lost in such an approach because estimation uncertainty is disregarded. We present a comparative method for exploratory repeated-measures analysis to complement the point estimates that was motivated by and is demonstrated by analysis of data from the CADET II breast-cancer screening study. The approach helped to flag up some unusual reader behavior, to assess differences in performance, and to identify potential random-effects models for further analysis.

  • 出版日期2011-12

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