Women who abuse prescription opioids: Findings from the Addiction Severity Index-Multimedia Version (R) Connect prescription opioid database

作者：Green Traci C^*; Serrano Jill M Grimes; Licari Andrea; Budman Simon H; Butler Stephen F

来源：Drug and Alcohol Dependence, 2009, 103(1-2): 65-73.

DOI：10.1016/j.drugalcdep.2009.03.014

• Gender
• Opioids
• Prescription opioids
• Substance-related disorders
• Surveillance
• Overdose

Background: Evidence suggests gender differences in abuse of prescription opioids. This study aimed to describe characteristics of women who abuse prescription opioids in a treatment-seeking sample and to contrast gender differences among prescription opioid abusers.
Methods: Data collected November 2005 to April 2008 derived from the Addiction Severity Index Multimedia Version Connect (ASI-MV(R) Connect) database. Bivariate and multivariable logistic regression examined correlates of prescription opioid abuse stratified by gender.
Results: 29,906 assessments from 220 treatment centers were included, of which 12.8%(N = 3821) reported past month prescription opioid abuse. Women were more likely than men to report use of any prescription opioid (29.8% females vs. 21.1% males, p<0.001) and abuse of any prescription opioid (15.4% females vs. 11.1% males,p<0.001) in the past month. Route of administration and Source of prescription opioids displayed gender-specific tendencies. Women-specific correlates of recent prescription opioid abuse were problem drinking, age <54, inhalant use, residence Outside of West US Census region, and history of drug overdose. Men-specific correlates were age <34, currently living with their children, residence in the South and Midwest, hallucinogen use, and recent depression. Women prescription opioid abusers were less likely to report a pain problem although they were more likely to report medical problems than women who abused other drugs.
Conclusions: Gender-specific factors should be taken into account in efforts to screen and identify those at highest risk of prescription opioid abuse. Prevention and intervention efforts with a gender-specific approach are warranted.

• 出版日期2009-7-1