Modified deep sclerectomy combined with Ex-PRESS filtration device versus trabeculectomy for primary open angle glaucoma

作者：Kozobolis Vassilios; Panos Georgios D^*; Konstantinidis Aristeidis; Teus Miguel; Labiris Georgios

来源：International Journal of Ophthalmology, 2017, 10(5): 728-732.

DOI：10.18240/ijo.2017.05.11

• modified deep sclerectomy
• Ex-PRESS drainage device
• trabeculectomy
• glaucoma

AIM: To compare the efficacy of modified deep sclerectomy combined with Ex-PRESS shunt versus trabeculectomy in primary open angle glaucoma.
METHODS: This is a prospective cohort comparative single-center study. Forty-nine eyes of 49 patients were enrolled in the study. Patients were randomly divided into two groups. Group A (22 patients) underwent classic trabeculectomy and group B (27 patients) underwent modified deep sclerectomy combined with insertion of Ex-PRESS model P50 drainage device.
RESULTS: Mean age was 69 +/- 7y in group A and 64 +/- 8y in group B (P=0.03). The mean reduction was 11.1 +/- 5.7 mm Hg in group A compared to 15.8 +/- 5.7 mm Hg in group B at 6mo (P=0.006), and 9.8 +/- 4.9 mm Hg and 15.4 +/- 4.7 mm Hg respectively at 1y (P=0.0001). Regarding the postoperative glaucoma medication, significant difference was observed between the two groups (in favour of group B) only at 6mo (P=0.017). At the end of the follow-up period complete success rate in group A was 68.2% compared to 92.6% in group B (X-2 test, P=0.07) and qualified success rate was 100% in both groups.
CONCLUSION: Modified deep sclerectomy combined with Ex-PRESS shunt may provide comparable IOP reduction with fewer complications in management of primary open angle glaucoma.

• 出版日期2017-5-18