Association of sperm morphology and the sperm deformity index (SDI) with poly (ADP-ribose) polymerase (PARP) cleavage inhibition

作者：Aziz Nabil; Sharma Rakesh K; Mahfouz Reda; Jha Rajesh; Agarwal Ashok^*

来源：Fertility and Sterility, 2011, 95(8): 2481-2484.

DOI：10.1016/j.fertnstert.2011.03.095

• Sperm morphology
• semen analysis
• SDI
• PARP cleavage
• apoptosis
• flow cytometry

Apoptosis was induced in immature and mature sperm in the presence or absence of poly (ADP-ribose) polymerase (PARP) inhibitor. The association of cleaved (cPARP) with sperm morphology was examined using sperm deformity index (SDI) score. The SDI scores are associated with PARP cleavage as an early marker of apoptosis. (Fertil Steril (R) 2011; 95: 2481-4.

• 出版日期2011-6