Amine-Controlled Divergent Reaction: Iminolactonization and Olefination in the Presence of a Cu(I) Catalyst

作者:Nishikata Takashi; Itonaga Kohei; Yamaguchi Norihiro; Sumimoto Michinori
来源:Organic Letters, 2017, 19(10): 2686-2689.
DOI:10.1021/acs.orglett.7b01020

摘要

alpha-Bromoamides arid styrenes underwent iminolactonization reactions (carbooxygenation), in which simultaneous C-C and C-O formation occurred in the presence of a copper catalyst with triethylamine as the base. Conversely, olefination reactions occurred in the presence of a Cu catalyst with piperidine as the base. The selectivities in those reactions were very high.

  • 出版日期2017-5-19