Associations Between Concentrations of Vitamin D and Concentrations of Insulin, Glucose, and HbA(1c) Among Adolescents in the United States

作者：Ford Earl S^*; Zhao Guixiang; Tsai James; Li Chaoyang

来源：Diabetes Care, 2011, 34(3): 646-648.

DOI：10.2337/dc10-1754

OBJECTIVE-Our objective was to examine the associations between concentrations of vitamin D and concentrations of insulin, glucose, and HbA(1c) in a nationally representative sample of adolescents in the U.S.
RESEARCH DESIGN AND METHODS-We used data for 1,941 adolescents, aged 12-17 years, who participated in the National Health and Nutrition Examination Survey between 2001 and 2006.
RESULTS-Adjusted concentrations of insulin were similar to 24% lower among male subjects with a concentration of vitamin D >= 75 nmol/L than among male subjects with a concentration of vitamin D < 50 nmol/L (P = 0.003). Concentrations of vitamin D were inversely associated with concentrations of glucose only among Mexican American male subjects (P = 0.007). No significant associations between concentrations of vitamin D and HbA(1c) were detected.
CONCLUSIONS-Our results support an inverse association between concentrations of vitamin D and insulin primarily in adolescent male subjects.

• 出版日期2011-3