Mild Oxidative Cyclization of Sydnone-Benzoylhydrazone with Lead Oxide to 2,5-Disubstituted-1,3,4-Oxadiazole-Sydnone Hybrid Derivatives

作者：Chiang Kuo Chen; Wong Fung Fuh^*; Hung Chih Hao; Huang Yu Ying; Chang Po Wei; Liao Yang Ming; Lin Shao Kai

来源：Journal of Heterocyclic Chemistry, 2009, 46(1): 111-115.

DOI：10.1002/jhet.21

The mild oxidation of sydnone-benzoylhydrazone hybrids with lead oxide in acetic acid/dichloromethane solution inducted their intramolecular cyclization to provide the corresponding 2,5-disubstituted-1,3,4-oxidiazole derivatives. The sydnone moiety has been efficient preserved for the future work in the mild oxidation.

• 出版日期2009-1
• 单位中国医科大学