A Practical Procedure for Efficient Synthesis of alpha-Amino Acids

作者:Liu Shouxin*; Ji Debin; Yang Yihua; Zhen Xiaoli; Tian Xia; Han Jianrong
来源:Letters in Organic Chemistry, 2009, 6(2): 156-158.
DOI:10.2174/157017809787582744

摘要

An effective method to prepare racemic alpha-amino acids was developed. The key reactions involve nitrosation of malonate under basic conditions and reduction of alpha-hydroxyimino ester derivatives with zinc powder in the presence of acetic anhydride.