Urine alkalinization may be enough for the treatment of bilateral renal pelvis stones associated with Lesch-Nyhan syndrome

作者：Oh Mi Mi; Ham Byeong Kuk; Kang Seok Ho; Bae Jae Hyun; Kim Je Jong; Yoo Ki Hwan; Yoon Duck Ki; Moon Du Geon^*

来源：Urological Research, 2011, 39(5): 417-419.

DOI：10.1007/s00240-011-0364-z

• Lesch-Nyhan syndrome
• Urine alkalinization
• Stones

Lesch-Nyhan syndrome is a rare sex-linked disorder of purine metabolism that is caused by a mutation in the hypoxanthine-guanine phosphoribosyltransferase (HPRT) gene which causes marked hyperuricemia and hyperuricosuria, with signs of gouty arthritis and uric acid stone disease in early childhood. We report a case of renal pelvis calculi which was dissolved within 10 days of urine alkalinization and hydration.

• 出版日期2011-10