Antibiotics and Probiotics in the Treatment of Diverticular Disease

作者：Tursi Antonio^*

来源：Journal of Clinical Gastroenterology, 2011, 45(4): S46-S52.

• diverticulitis
• diverticulosis
• antibiotics
• 5-aminosalicylic acid
• mesalazine
• probiotics

Diverticular disease is one of the most common diseases of Western industrialized countries, and it may be associated with numerous abdominal symptoms (including pain, bloating, nausea, diarrhea, and constipation). Although antibiotics are the mainstay treatment for patients with acute diverticulitis, these drugs are still recommended for patients with uncomplicated diverticular disease. Changing concepts on pathophysiology of the disease suggest that diverticular disease may share many of the hallmarks of the inflammatory bowel diseases. On this basis, a new therapeutic approach based on mesalazine and probiotics may enhance treatment efficacy in shortening the course of the disease and in preventing recurrences.

• 出版日期2011-4