Assembly, postsynthetic modification and hepatocyte targeting by multiantennary, galactosylated soft structures

作者:Thomas Anisha; Shukla Akansha; Sivakumar Sri; Verma Sandeep*
来源:Chemical Communications, 2014, 50(99): 15752-15755.
DOI:10.1039/c4cc07074g

摘要

Enzyme modifiable, hollow self-assembled structures offer an excellent scope for multiantennary delivery vectors. Herein, we report synthesis and applications of bis-galactose lysine based supramolecular ensembles, which possess surface galactose moieties amenable to enzymatic modifications. This post-synthetic modification generates reactive aldehyde groups, which could possibly serve as dynamic anchors for crosslinking and cell adhesion.

  • 出版日期2014