A facile one-pot regioselective synthesis of functionalized novel benzo[f] chromeno[4,3-b][1,7]naphthyridines and benzo[f][1,7]naphthyridines via an imino Diels-Alder reaction

作者：Arepalli Sateesh Kumar; Park Byeongwoo; Jung Jae Kyung; Lee Kiho; Lee Heesoon

来源：Tetrahedron Letters, 2017, 58(5): 449-454.

DOI：10.1016/j.tetlet.2016.12.050

• 13H-Benzo[f]chromeno[4,3-b]
• [1,7]naphthyridines
• 1,3-Diphenylbenzo[f][1,7]naphthyridines
• Imino Diels-Alder reaction
• Atom economy
• One-pot multicomponent reaction

A novel series of functionalized 13H-benzo[f]chromeno[4,3-b][1,7]naphthyridines and 1,3-diphenylA-benzo[f][1,7]naphthyridines have been synthesized by an efficient regioselective one -pot multicomponent synthesis through intra and intermolecular imino Diels-Alder reaction. In this method, we have achieved complete regioselectivity and atom economy with polysubstituted core motifs in moderate to good yields. The proposed mechanism of this reaction has also discussed.

• 出版日期2017-2-1