A novel fluorescent probe based on the flexible dipicolylamine: Recognizing zinc(II) in aqueous solution and imaging in living cell

作者：Zhang, Na; Tian, Xiaohe; Zheng, Jun; Zhang, Xiuzhen; Zhu, Weiju; Tian, Yupeng; Zhu, Qiyong; Zhou, Hongping^*

来源：Dyes and Pigments, 2016, 124: 174-179.

DOI：10.1016/j.dyepig.2015.09.019

• DPA
• Probe
• Recognition abilities
• Zinc ion
• Fluorescence spectra
• Cell imaging

A novel fluorescent probe for Zn2+ has been designed and synthesized based on a dipicolylamine group connected by a benzimidazole amide backbone. A comprehensive analysis of the recognition ability of the probe towards metal ions was conducted by ultraviolet absorption and fluorescence emission spectroscopy. Results demonstrated that the probe showed selective and sensitive fluorescence turn-on signaling behavior toward Zn2+ in HEPES buffered (pH = 7.4) aqueous solution. The detection limit of this probe was calculated to be 5.10 x 10(-8) M for Zn2+. Fluorescent imaging inside HepG2 cells indicated potential application of the probe for detecting Zn2+ ions in living cell imaging.

• 出版日期2016-1
• 单位安徽大学; 淮南师范学院