摘要

In this paper, we propose the graph energy of 20 amino acids and the 2D graphical representation of protein sequences based on six physicochemical properties of 20 amino acids and the relationship between them. Moreover, we could get a specific vector from the graphical curve of a protein sequence, and use this vector to calculate the distance between two sequences. This approach avoids considering the differences in length of protein sequences. Finally, we research the similarities/dissimilarities of ND5 and 36PDs using our method and get better results compared with ClustalX2.