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摘要
Objectives: Acute pancreatitis (AP) is one of the most common and severe diseases in gastroenterology. The main pathological characteristic of AP is still unclear. This study aimed to analyze the pathogenesis and clinical features of AR Methods: The clinical data of 609 hospitalized AP patients were collected using the EpiData single-disease data software. The general condition of the patients, the etiological factors and causes, the clinical symptoms and signs, laboratory and imaging examination, the severity and complications were analyzed using SPSS 13.0 statistical software. Results: The main causes of AP are biliary disease (35.9%), hyperlipidemia (26.3%), idiopathic pancreatitis (22.7%), and others (15.1%). The patients of biliary pancreatitis are mainly elderly. Patients with hyperlipidemic pancreatitis are mainly young and middle-age. Among the 609 AP patients, heavily drink and overeating were in 44.5% of the patients, and obesity was in 35.5%. The main clinical symptoms are acute persistent upper abdominal pain (95%), mostly accompanied with ventosity, nausea, vomiting and other gastrointestinal symptoms. Serum trypsin level significantly increased in most of the patients. More than three times of imaging examinations were performed in all patients. The common complications of AP include intestinal paralysis, abnormal liver function, pleural effusion and pulmonary infection. Conclusion: The major risk factors of AP for middle- and old-age persons are biliary pancreatitis, while obesity and hyperlipidemia for the young persons. Heavy drinking and overeating are the main causes. The dynamic CT and laboratory examinations are the main measures to determine the severity and complications of AP.
- 出版日期2018
- 单位南方医科大学
